Methods
- Automated behavioural testing of emotional, motivational and cognitive processes in mice
- Environmental stressors
- Adeno-associated viral vectors for stress factor over-expression e.g. Corticotrophin releasing hormone; Pro-inflammatory cytokines
- Genetically-modified mice: Serotonin transporter (slc6a4) knockout; TNF receptor 1 (Tnfrsf1a) knockout; Potassium channel tetramerization domain-containing protein 12 (Kctd12) knockout
- Stereotactic surgery
- In vivo microdialysis
- Neuropsychopharmacology
- Biomarker analysis in brain, cerebrospinal fluid, blood and faeces (ELISA)
- High performance liquid chromatography and tandem mass spectrometry (in collaboration)
- Neuroanatomy (Histology, in situ hybridization, immunohistochemistry) (in collaboration)
- Quantitative molecular genetics and epigenetics (DNA methylation, Transcriptome microarray expression profiling) (in collaboration)
- Magnetic resonance imaging of neural activity (in collaboration)
